In this circumstance 99mTc-CTMPcould interact withcalcium carbonate and cholecalciferol and it might then interefere with the imaging results. Therefore, it could be used as bone tracer (radiopharmaceutical) in bone imaging.However, there has been a concern regarding the use 99mTc-CTMPon patients who have been treated with calcium carbonate and cholecalciferol. Tc-99m radiolabeled 1,4,8,11-tetraazacyclo tetradecyl-1,4,8,11-tetramethylene phosponic acid(against 99mTc-CTMP)on the other hand is a radioactive complex compound which has an affinity toward bone. Hypocalcemia is one of manifestation of bone metastases which could be treated using calcium carbonate and cholecalciferol.
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